My preference is for the buckmark though ruger makes a fine gun also. I prefer the grip and trigger of the buckmark. I know it is less durable, but it's also relatively inexpensive. If I have to replace it after 15 or 20 years, I don't care because it's a 200 dollar gun. I've had mine for 5 years and no problems yet.
Buy whatever 22 you like best. I wouldn't hesitate to spend 600 bucks on a 22 if it was the one I really wanted. It comes down to it, that 22 will probably be the gun you will shoot most. It will be the gun you use to introduce friends to shooting who have never been before. It will be one of the last guns you well if you go broke.
An option which hasn't been mentioned here is a 22 revolver. Not the best for training for you 45, but great fun to shoot with or without scopes. Smith makes a very fine but pricey 22 revolver. Ruger makes some inexpensive quality single action revolvers. The neat part about the rugers is that many of them come with both 22LR and 22WM cylinders.
So anyway, buy whatever 22 you like best, experiment until you find it's favorite ammunition, and then enjoy it...