I've put several hundred rounds on the newest revision of printed buffer with very little damage to it. My problem is that I'll revise the design before I get any large round counts on any one part before exchanging it for an updated and improved version. 800 rounds seems like a pretty reasonable guess for the failure point of a printed buffer. I should have samples of the production buffer (probably around 50 or so) in hand within a week, and I'll probably release some for testing to a few folks here as we work on producing a bunch of them. They're being molded using a rubber toughened grade of delrin that has great impact strength. The printed plastic should prove to be vastly inferior to the production models, so hopefully we'll see 1000+ rounds to failure per buffer. They are a wear item, but I'm shooting for less than a quarter cent per shot cost to run the production buffers.
As far as a left handed upper, worst case you'll have to clip the little alignment tab off to make it fit. Best case, the cutout on the rear of the bolt is still on the same side and it will drop right in.