If i am understanding your questions correctly, the top "big screw" is designed only to retain the piston. Screw it all the way in, then back it off until the ball detent rests into the locking grove. The line cut into the hex socket should be nearly vertical.
Concerning the little screw, if you screw it all the way in clockwise, this is fully closed, no gas allowed into the gas tube, single fire only. if you then back it out 4.5 turns, the gas block is fully open. This is just like 90% of the standard gas blocks out there at this point. If oyu have set the detent at 4.5 out, your rifle should function at this point.
if you then continue to back the set screw out more, the block will start bleeding gas out the front of the block, instead of simply restricting or halting it in the barrel (often gas is pushed back into the receiver via the barrel as it has no place else to go). This is very helpfully for suppressed guns, lefties, and reducing gas to the face. But the gas allowed through the valve effects the rifle about the same either way.
I am not sure of your skill set, and please do not take any offense, as non is intended. I do strongly recommend you double check your block to make sure is it centered and seated properly. block alignment is critical to correct gas flow. Also, make sure you have a standard buffer spring and H1 buffer. The point behind heavy buffers is to reduce kick back because most rifle, including carbines, are over gassed. A heavy buffer slows things down a bit, But a piston gun, with an adjustable block, will not need a heavy buffer or spring.
Also, sometimes both the set screw model and clamp on model can shift during install. If the gas block covers the gas port on the barrel at all, you will have problems from the start.
Normally I would recommend a clamp on model gas block. But this is a piston gun. The set screw model has a slot cut to pin the block. Once you have you rifle dialed in, shoot it, and decide the piston system is the way to go for you, find a good gunsmith and pay them to pin the block. If you do not pin your gas block on a piston rifle, it WILL eventually come loose. Not the end of the world for a fun gun, but a big deal if your life depends on it. If you would prefer to pin it yourself, Brownells sells pins, jobber dril bits, and taper bits, its about a $30-35 dollar project fro the DIY'er.
BUT, take your time, go slow, and make sure you have a good vise on a drill press or a drill chuck on a mill. And some cutting oil. The gas block is hardened stainless, it take a slow cut to work through the metal.
I use the SA pistons on all of my SBR rifles, 10.5" 5.56, and 8-8.5" 300BLK. If you run subs on the 300BLK, you may need to open the gas ports up a bit and then dial them back down with the detent on the gas block.
If you check everything, all aligned right, standard spring an buffer, and you still have issues, you can always open the gas port on the barrel a bit. But honestly, you really should not need to do that on a 10.5" carbine barrel.
Let us know how things turn out.