The bullpup concept is supposed to offer a couple of advantages over a conventional design. However, in light of recent developments, those advantages may no longer exist.
[b]1. Shorter overall length without having to collapse or fold a stock.[/b] While this may have once been an advantage, it is no longer. The collapsible stock of the CAR-15/M-4 used to be disparaged because you only lost 4-6" of length from a fixed stock and it wasn't as compact when collapsed as a folding stock. Now with chest rigs, body armor, etc, the ability to adjust the stock length to accomodate what you're wearing is seen as a big advantage. Take a look at the stock of the XM-8. It can fold, but it can also collapse to adjust the length of pull.
So, while the short length may still be a desired feature, the lack of adjustability is a detraction.
[b]2. Barrel length.[/b] This ties in with the shorter overall length, but the idea was you could have a rifle length barrel (20") in a carbine sized package. This is still true, but you have to ask yourself why you want a longer barrel. A longer barrel gives you greater velocity and in some cases, a longer sight radius. Since 55gr and 62gr 5.56mm are very dependent on velocity for fragmentation and upon fragmentation for lethality, this is a valid consideration. But it appears that the 77gr bullet provides fragmentation and lethality at lower velocities. Consequently, with the right type of ammo we may not need the extra length/velocity.
[b]3. Ergonomics.[/b] This is the biggest disadvantage of the bullpups and it is one that both covers a lot of territory and is still unsolved. Bullpups usually have poor balance, being very muzzle light. As others have said, they are slower to reload than the AR15/M16. They require substitution of parts to switch from a right handed shooter to a left handed. This can be an issue when shooting around corners, shooting from the weak side if you receive a wound on the strong side, or say a lefty has a damaged or non-functional weapon and he has to pick one up on the battlefield. Only the FN2000 has addressed this issue. But, has anyone tested it shooting upwards, as in clearing a stairwell? How well does forward ejection work when gravity is an issue? Anyone think you might get a stoppage that could be difficult to clear?
[b]4. Added equipment.[/b] Face it, the days of a bare rifle are almost gone. Day optics, night optics, laser designators, grenade launchers, flashlights, bipods, etc. The etc. is 'cause I'm sure some of you can think of other things to hang on it :)
The bullpups are usually lacking in forward real-estate for all this gear, though I'll say if a GL can be mounted, it probably improves the balance while providing a better handguard.
[b]5. Value to cost.[/b] Finally, what do you gain for what you spend? I don't think there is a bullpup design in existence that offers a net increase in performance over the M4/M16 series sufficient (if there is one) to justify the cost of switching over.