No question, no hesitation. It's the same as my answer when a non-gun person asks about a handgun for the home or car: S&W Model 10 (or predecessor/successor) in .38 Sp., unless weight is an issue, in which case go with a Model 37 (or predecessor/successor) in .38 Sp. if weight or size is an issue. You lose one round, one pound, and about 3" with a 37 series.
They are accurate and the controls are instinctively accessible. They are idiot-proof and as close to abuse/storage-proof as a gun can be. If they're loaded, they'll go off when you pull the trigger, even if they've been gathering rust, dust, and goo in a purse or drawer for decades. Parts availability is incomparable (I can't imagine how many millions of the things are floating around) and ammo is cheap. They are also very nice pieces of machinery.
When I see one, if the price is reasonable and I have the money, I buy it. I have probably given away 10 of them over the years. I picked up a very nice 2" Mod 10 with stag handles for $197 out the door a week or so ago. IMO, they are like toilet paper, AR mags or duct tape: you cannot have too many, and you can't waste money buying them. They are just that useful - especially if you are "the gun guy" in your circle of acquaintances. It's nice to be able to put one in a woman's hand 15 minutes after she comes to you terrified by a string of rapes or what-have-you in her neighborhood.
They are certainly not the "ultimate" gun (what is?), but as far as utility and effectiveness they deserve a place in some museum of design. They are the apotheosis of that particular line of tools.