A far more interesting little tidbit is how the "little ice age" in Europe influenced the situation in CONUS.
The same mechanism ( atlantic current slowing) that plunged europe into bitter cold, froze the Thames in the wintertime and made beer the drink of choice in most of Europe (when the grape vines died), also had disasterous effects in the eastern US. Coastal tribes diminished, and the largest cohesive civilization in the new world at the time, the greatest military power, the Mississipians, who had cities of up to a million people, flood plain agriculture, and a sophisticated water transportation network, were decimated by centuries of brutal storms and flooding which ruined crops, year after year. So when the Europeans arrived there were only scattered tribes of hunter/gatherers where there had been a civilization of millions. However technologically backward they may have been a cohesive civilization such as the Mississipians would have made colonization a much slower, more difficult process, so much so that it's likely they'd still be recognized as a nation today, or alternatively there would have been an epic war for the region.
None of that has any bearing on current policies or politics, and neither does who gave what bugs to who, but it is interesting. Civilizations rise and fall, European civilization caught a huge break finding the Americas in such a weakened condition, and other civilizations will be there to capitalize on our misfortunes as well.