This is a tricky question for anyone to answer. Under perfect conditions, FLIR works really well. At any other time, it all depends on how much experience the operator has looking at the display.
Like ARDunstan said, it's not RADAR, but it still is Electro-magnetic Radiation.
Here's our Physics lesson for the night. Light doesn't technically reflect in the way you think it does. Light (EMR) is actually retransmitted, and that's what we see. Same thing with FLIR. The tuned EMR is retransmitted by the object the EMR illuminates. THe sensor then picks up this retransmission and software makes sense of it all for the operator to decide what he's looking at.
So, if you know what the frequency is, all you have to do is to make sure whatever it is you're wearing or hiding behind can't retransmit that frequency.
Like iamblades said, Glass cannot retransmit infra-red or ultra-violet (that's why glass houses are hot; since the glass cannnot generate enough energy to retransmit either IR or UV, it just gives off heat instead;) you can hide behind glass, and not be detected by an active infra-red system. But they have other things for that.