FRIDAY, Jan. 23 (HealthDay News)

The first human trial using embryonic stem cells as a medical treatment has been approved by the U.S. Food and Drug Administration.

Geron Corp., a California-based biotech company, has been given the OK to implant embryonic stem cells in eight to 10 paraplegic patients who can use their arms but can't walk. Stem cell injections will be given within two weeks of the injury. The study will begin this summer, and will be conducted at up to seven different medical centers.

"This marks the dawn of a new era in medical therapeutics," Dr. Thomas B. Okarma, Geron's president and CEO said during a Friday morning teleconference. "This approach is one that reaches beyond pills and scalpels to achieve a new level of healing."

Ultimately, this type of therapy might have the power to restore permanent organ and tissue function, Okarma said. The goal of this first trial is to see if injecting embryonic stem cells into humans is safe. However, the researchers will also be looking for signs of improvement in the patients' ability to feel sensation in or move their legs.

Patients will receive injections at the site of the injury. It is hoped these cells will mature into cells that will repair damaged nerves and produce chemicals that nerve cells need to function and grow.

This phase I trial will be limited to patients whose injury is located in the middle of the spine. If the trial is successful, Okarma said, the hope is to extend the treatment to patients with cervical spine injuries who are paralyzed from the neck down.

Okarma said the injections must be given early after the injury, before scar tissue has developed that would prevent the cells from growing, but after the initial swelling has subsided.

In addition, patients will receive anti-rejection drugs for about two months, after which they should no longer need those drugs. Patients will be followed for at least one year, he said.

The treatment is not expected to restore full function to patients, but the researchers hope to see modest gains. "Any return of bladder or bowel function, a return of sensation, or a return of lower extremity locomotion would be a very exciting finding," Okarma said.

In experiments with rats, researchers found these cells were safe and did restore some function. "These cells insulate as well as stimulate nerve fibers, leading to restoration of function in animal models of spinal cord injury," Okarma said.

The cost of this therapy isn't known yet, but Okarma said it would be "affordable."

Embryonic stem cells are the most basic human cells. These cells are believed to be capable of growing into any type of cell.

The controversy surrounding the use of these cells has become a political issue, with some objecting that the use of these cells destroys potential life because they must be extracted from human embryos. This belief resulted in the Bush administration banning federal funding for embryonic stem cell research.

While the Obama administration has indicated that it will lift the ban, the stem cells used in this trial were obtained from one of the Bush administration's approved stem cell lines. However, no federal funds were used in the development of this treatment.

A decade has passed since the first embryonic stem cells were isolated at the University of Wisconsin, in groundbreaking research that was funded by Geron Corp.

Geron is also working on using embryonic stem cells to treat failing hearts and to create insulin-producing islets for type 1 diabetics, Okarma said.

"Embryonic stem cells are really nature's own way of making more of ourselves," Okarma said. "We are simply harnessing the biology of normal human development in our attempts to achieve permanent cures to chronic disease and injury."

Peter Kiernan, chairman of the Christopher And Dana Reeves Foundation, said he's excited about this latest development in stem cell research.

"This is not just a comet across our sky, this is really more like dawn," Kiernan said. "We are beginning a vast human experiment, and we have been waiting an extremely long time to get to this point. This is a very significant development."

Quoted:
YEAH BABY. I'm holding big and waiting.

I posted a stock tip in GD a couple of months ago and got FLAMED!!!!!!!!!

The next morning the stocks I suggested were up over 30%

Since I don't learn from my mistakes here they are again.

ASTM

STEM

GERN

I'm looking to score when the Kenyan opens the federal funding floodgates.
Which I don't agree with by the way.

ETA: YEAH!!!!!!!!!!! ASTM already up over 20% today !!!!!!!!!

Quoted:


but yet funding. You heathen scumm. (off to buy stock in all three)

Quoted:
That spike was me buying.

Quoted:
an abundance of caution

Quoted:
We're gonna have a race of fucked up mutants runnin' around before long, tamperin' with mother nature like this!

Quoted:



What are you? Some sort of anti-mutant Zombie hater? What are we gonna shoot with our $2k bone stock ARs and $100 10 round magazines  5 years from now if they dont get cracking on making a race of fucked up mutants, who eat flesh btw.

Quoted:

I'm all for it, you do know that embryonic stem cells are harvested from a blastocyst 5-7 days post fertilization? That looks like this:


http://www.advancedfertility.com/pics/blastocyst.jpg


Nothing even closely resembling human life.

Quoted:
We're gonna have a race of fucked up mutants runnin' around before long, tamperin' with mother nature like this!

Quoted:

I'm all for it, you do know that embryonic stem cells are harvested from a blastocyst 5-7 days post fertilization? That looks like this:


http://www.advancedfertility.com/pics/blastocyst.jpg


Nothing even closely resembling human life.

Quoted:


The next 2 pictures in that sequence:

11 weeks post fertilization:
http://farm3.static.flickr.com/2144/2177341808_cd2513d41c_m.jpg

22 weeks(?) post fertilization:
http://farm3.static.flickr.com/2006/2266385408_1de0d11dc7_m.jpg

They don't really look like human life either.  the second one looks like a frigging V baby!  (does anyone even get that reference?)

Quoted:PEOPLE!  This thread is juuuuuuuust now starting to go in a possibly "south" direction.   Let's try to take it somewhat easy on eachother.

Quoted:

With BHO in office we can finally return our rights to post-term abortion.  I mean if it's ok three months before birth, why not go three month afterbirth?  Of course this would only be in cases where the baby was a great inconvenience to the parents...

Quoted:



You are right, sir!  This unbridled tampering with the forces of nature will cause the Zombie apocolypse we've all only known as fiction...................and you are correct, sir, let us boldy embrace our fate, as we stare down the mindless hordes, not to utter "oh no," but to shout "FINALLY!".

Quoted:

...................a clone is only a copy on the cellular level, the DNA itself.

Quoted:



Officer, I didn't commit the crime where you found my DNA and fingerprints... My clone did it...

Quoted:


I lol'ed... this is so true... So... Where would we all hold up... What would be your ideal place to be when the zombie hordes come...

Me: Someplace where there are other ppl with guns and lots of ammo...

Quoted:
They don't really look like human life either.  the second one looks like a frigging V baby!  (does anyone even get that reference?)