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I am not sure a 5.56 rifle is the best caliber for taking an Antelope. While legal in the regs, there are some bullet requirements. A 243 or 25:06 would be a better choice or a 308 AR IMO. You only want to use one shot as there is only so much meat on them and you don't want to waste it.
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I'd generally agree and I've actually posted that I thought that big game hunting with a .224 bullet is more of a stunt than a sport, but I've recently changed my mind...
My grown daughter has decided to keep my .270 as a memento. She has called it 'her rifle' for a long time anyway. If I decide to hunt with her, it will come down to a choice between my elk-hunting 300 Win Mag loaded with 200grain Partitions and my handy 16" AR-15 and a premium bonded bullet. My vote goes with the AR15. It has a military 10X scope with a mil-dot reticle and mil knobs. I have no doubt of my ability to place a shot but I'd confine my hunting inside 200 hundred yards or so due to terminal velocity. If I can't place the shot correctly for the limitations of the cartridge, I won't take it. Another thing in favor of the AR is that 2nd shot followup is quicker. I'm not talking about semi-auto hunting - I'm talking about recoil management. By the time I regain the sight picture with my 300 Win Mag and locate my target, I may have lost the opportunity for a quick followup shot.With my AR, I can see the bullet impact and watch what happens. Whatever the caliber, one-shot "bang-flops" are only a sometime thing anyway.