I Heard and became obsessed with the .45 super in 1994. I think most of us see foot pounds & fps and start drooling. Things happened in my life that set the idea on the shelf (one of which being the AWB) and Only a handful of times has that prarie dog stuck its head out of the hole.
I have this talent for writing Homerian epics, so let me trim the BS...
NO.
1. .45 Super is like 10mm for all the good/bad reasons except it is MORE of a PITA (in terms of ammo supply & cost). Plus, IIRC you MUST have the .45 worked on because the chamber pressure is too much for standard .45 layout.
2. .45 super 10mm is a bad choice for a gun. If this causes foam to form at your mouth then take a deep breath and add the worfs "for me" at the end of the last sentence. Like the .44, its a matter of overpenetration/overkill. Recoil has to be a bitch. I have a hard enough time as it is practicing with ball. I can scarcely afford to practice with JHP, which is to my detriment. I would really be in the shitter coming up with the $ to practice with .45 super and a pistol that "advanced" (recoil wise) would really throw me off my game.
3. It's been in existence in my world for more than 10 years and I haven't seen it take off, nor any special need for it yet.
If you want something "over the top" consider a 1911 chambered for 10mm, unless you just want to be different, and if you have the time, $, etc. there's nothing wrong w that.