On my guns I've had two safety failures, both at the joint. On guns that I've worked on, I've seen failures of safeties (same as above, as well as lever breaking off), slide stops, firing pin stops, and a couple hammers. I was talking to the head armorer of Maricopa County Sheriff's Office yesterday, and he has seen a few safeties with sheared off internal studs on duty weapons Quite a few deputies, himself included, carry Kimbers, but they have seen very few MIM failures.
I'm sure others will chime in, but I've seen people post with much more disturbing MIM failures, such as barrel bushings and mainspring housings. I say these are more disturbing simply because you would not expect these things to break, and I've never seen a non collet bushing break.