First off, the idea that parents are responsible for paying all college expenses is absurd. Your friend can and will have to help, but it isnt his sole responsibility. The daughter needs to understand that and accept the fact she will owe a lot of money post graduation.
Now, my advice and experience:
Try to avoid student loan debt as long as possible. This means living at home and doing her premed at a local state university if possible. I was lucky to have a 4 year state university locally, living at home cuts expenses dramatically. She should pursue any scholarships, grants, etc available, and be willing to work part time if possible. I paid all of my prepharmacy education without taking out any student loans.
Once she is in medical school, she will need to borrow money via student loans since it is unlikely she will be able to work much while school is in session. The trick is not to overdo the debt. This can be done if she is realistic about budgeting, and she does not have monthly debt like car payments. Her father can help with groceries, car insurance, reasonable spending money as he can afford it, etc. I qualified for enough loan money to cover most of my living expenses in addition to tuition/books/fees, and worked during Christmas/spring break/summer break. She should aggressively pursue any grant or scholarship money available also, there is a lot available once you are in medical school.
My basic goal was to graduate pharmacy school owing no more than one year gross salary in debt. At the time of my graduation (1996) this was around $60k, and I borrowed a total of $54K over 4 years. I have paid most of it off already and should finish a year early. The standard repayment plan for student loans is 10 years, extendable to 15 or 20 years under certain circumstances. If she plans for a 10 year repayment plan and defers repayment until after her residency, it is a managable debt load. Most recent grads dont realize it, but it will take her 2-5 years to really get herself financially grounded after school is finished. She should plan accordingly, even if that means putting off the big house and H2 for a few years.
Hope this helps.