I just did a shitload of research on tires for my Sierra Denali - and went with Michelin LTX Defenders at Costco. I don't even remember what tires I had on it, but the Defenders are a HUGE improvement in ride, and very quiet. 70k or 80k treadwear warranty.
The Defenders are the next iteration/generation of the LTX M/S 2 tire, which was arguably the best overall all-season/highway tire.
I run LT245-75R16 load range E tires on my Suburban 2500. They are a little smallish, but I don't want to put any additional stress on suspension components with a lift and/or bigger tires. I beat the snot out of that truck pulling trailers as heavy as 8600 lbs. I honestly don't get the whole lift/big tire thing - you're intentionally overstressing driveline and suspension components, causing them to fail prematurely, just to have a certain look/stance?
The truck fora I frequent are littered with threads about shimmies, shakes, vibrations, grinding noises, rubbing, bad CV angles, etc - just to get the brodozer look?