...scene to Mass Effect 2.  I dont want to give away any spoilers, but those of you who have played it know what I am talking about.  Then scene on the Normandy blows me away every time, and I am on my 5th play through since it came out last year.  In my opinion that is one of ,if not the very, best opening scene in any game I have ever played.  I am really looking forward to ME3, from what I saw in Game Informer it looks great.  I think there are going to be some insane battles in it, given the fact that you are recruiting entire armies to fight for you.