I drove a 96 F250 4X4 until it had about 250,000 miles, it was a company owned vehicle, so it had had oil changed every five thousand miles, and all regular maint done at the proper intervals.  When it was retired it was running and driving very well. At about 175K I had a bunch of work done on the suspension (new shocks and springs all the way around), and had some chassis parts that were factory riveted tightened up by having the shop drill out the stretched rivets and putting in bolts. That vehicle never had any major troubles at all. It would have kept going forever with good maint. This was a gas vehicle by the way.