Saw this posted somewhere on a medical forum. Thought it was interesting because we had a discussion about this some months back:


"When drinking, aspirin can be very dangerous and quite poisonous.  Aspirin should never be taken before, after, or during a drinking session.  Alcohol already irritates you gastrointestinal tract and aspirin just increases the acidity that can cause internal bleeding.  The AMA published an article stating that taking an aspirin before a night of drinking can increase the blood alcohol levels by 26%, thus prolonging the presence of alcohol in your system.

Check out this article from the University of Pennsylvania School of Medicne:    

"Acetominophen, Aspirin, and Ibuprofen should never be taken with alcohol (unless directed by a physician). Alcholics even should avoid them when not drinking. Tylenol is metobolized by the liver and if the liver has upregulated p450 enzyme system it releases a toxic metabolite. Alcohol plus acetominophen has led to numerous liver transplants and is very dangerous. Recently, Tylenol has been forced to put labels on their bottles with alcohol warnings. Ibuprofen is also metabolized by the liver and little may be known. However, alcohol is a stomach irritant and NSAIDs like aspirin and ibuprofen plus alcohol is also a bad idea."  
"

Can you say Liver Failure?

Ibuprofen, Aspirin and Motrin should also not be taken if you have been infected by beta strep A. This can lead to Necrotizing Fasciitis or commonly called "flesh eating bacteria".

That's not a good hangover solution anyway.

Best solution is don't get wasted.

Otherwise, drink a couple of quarts of water before bed, keep a quart by your bed so you'll have it during the night, then in the morning, drink another quart, eat a light meal, and then take the aspirin. At least your stomach had some time to heal during the night and the fact you have some food in your gut helps it from getting tweaked by the aspirin.

I know about this stuff. I was a professional drinker during my school years.