I'm thinking about purchasing a large caliber REVOLVER. I want something in a pistol caliber (ie forget the .45-70 "Golden Bison" revolver). I'd prefer double action and a cylinder that comes out of the frame for reloading (don't remember the proper term for that), but I'm willing to look at any revolver y'all bring up.
I'm only considering modern arms and cartridges; no blackpowder, percussion, etc. Thus far, I've looked into the .44 magnum, .454 Casull, and the .480 Ruger. Any other nominations? If so, know what manufacturer makes a handgun for them?