These are super popular in high power for the 600 yard stage.
Many 5.56 and Wylde chambers will fit these fine, as well as some .223 chambers. Some will not. You pretty much have to check you individual gun. These are generally loaded about as hot as the .223 is made to go and bullet setback is a potential risk. Even though these bullets are longer, most of the length is in the ogive.
If you get a box and try them in an AR make sure your bolt is closing easily.
The only advantage these have over the 77 grain projectiles is the longer bullet shape and better long range ballistics as a result. The trade off is that they don't fit in AR magazines, but will fit in most short action bolt gun magazines. The faster twists are pretty much required, although that again comes down to individual gun, as long barrels can sometimes get by on slower twists.
I don't have my reloading log book handly, but my 80 grain handloads made to match one of my rifle's chambers is a very long projectile for the .223. I can't remember off the top of my head, but it made 55grain FMJ's look like short stubby rounds.