moa is roughly i inch at 100yds. It stand for minute of angle or minute of arc depending on who you speak with. Generally in small arms we speak in minutes of angle, artillery would be minutes of arc. A one moa dot would cover 1 inch of the target at 100yds. It would be 1/2 inch at 50yds and 1/4 inch at 25. You mutiply the moa times the distance in yards. So that same dot would cover 2 inches at 200yds, 5 inches at 500yds, and 10 inches at 1000yds, The main thing to consider when picking an optic in reference to the dot size is the usage of the firearm. If all of your work will be within 200 or 300 yards, you would want a larger dot. Larger still if most of it would be in cqb type situations. The larger dot will be easier to pick up on and should be faster. My personal preference is the standard eotech reticle because the dot size is imoa, allowing for precise and longer range shooting, while having a circle around it that makes it quick to pick up with the eye and get on target at closer ranges. It , the 65 moa circle ,can also be used as a range estimator.