God damn there's a lot of BS in this thread! One of the best resources on the internet for terminal ballistics is right here on this forum!
"Best Choices for Defensive Ammo by Dr. G. Roberts"
1.) Hollow point and OTM are 2 different things. OTM rounds are match rounds which are formed from the base up. This is done to give the bullet more consistent flight characteristics as the trailing edge of the round has more impact on the flight than the leading edge. It just so happens that heavy OTM type bullets are the most effective 5.56 rounds available for defensive use.
2.) Exotic handguns rounds (ie the Glaser Safety slug and the like) have proven time and time again to be nothing more than a marketing hype and woefully inadequate compared to high quality hollow point rounds from Federal, Hornady, Remington, etc.
3.)Varmint rounds are just that, varmint rounds. I don't care if Hornady puts a pretty red plastic tip on them and calls them "TAP" rounds, they are meant for small thin skinned game and not humans.
4.)The only shotgun round that should be seriously considered for use in a home defense situation is buckshot. Slugs grossly over penetrate and therefor should not be used indoors. Birdshot is for birds, it does not penetrate deep enough to cause immediate incapacitation. Buckshot, 00 or #4 over penetrates worse than 5.56 rifle rounds. It is a poor choice if you're worried about that sort of thing.
5.)Pistols are very difficult to use under stress for 1, and for 2 if a pistol is fired and hits drywall (assuming your using a JHP...FMJ has no business being used for defense and hasn't for nearly 30 years) the hollow point cavity will plug with building material causing the round to over penetrate like a FMJ.
The question is not "will this go through drywall?" Heck a Red Ryder BB gun will go through a wall, the question is as Zhukov stated, what damage will that round do once it has gone through that wall.
One of the most comprehensive terminal ballistics forum on the web...
You can believe what ever you want to believe, however this post reflects the most accurate and current data on the web.