I'd suggest timing the pick-up so that it's complete before you check out of the hotel. It'll make that aspect much easier.
You can have a firearm unloaded and in a locked container in your vehicle without restriction. Mags can be loaded. Mags and ammo can be in the same container, or be unlocked, on your person, etc. The container can be in the main compartment with you and accessible. Can't use the center console or the glove compartment, although a lock box fixed to the inside of the center console is apparently okay now.
As was mentioned, California has a 4th Amendment "exception" for guns to see if they are unloaded. I, too, would suggest not having the container be visible unless it's not something that looks like a gun case (like a locked compartment in a backpack or something). I would not tell an officer about it. California is not a duty to inform State. No good can come from that, even if nothing bad happens.
For travel outside of a vehicle, you can't just carry the gun this way. There are destination requirements, such that you can only carry it unloaded in a locked container going immediately to and from your home, other private property where you have a right to be, the range, an area where shooting outdoors is legal, a shooting competition, hunting, an FFL, from car to indoors and vice versa, etc.
Your hotel is treated like your residence, so you can have it loaded, carry it however you want, etc. inside of the hotel room.
There are some exceptions to the above, but they aren't going to apply to you on this trip.
Make sure your guns do not have threaded barrels (that makes them assault weapons).