IMO, it's a good practice to get into to point your thumb at the target.
When you draw, your thumb is pointed at the target. When you raise the firearm, your thumb will be pointed at the target... and will have magically swiped off any 1911-style safety that's there.
If you practice this way, you'll never have a problem with the safety, and if the gun doesn't have one, you'll never have a problem with that, either.
The caveat is that if you have something like a Beretta 92, with a slide-mounted safety, you are potentially flipping it the wrong way. But really, those are pretty hard to accidentally manipulate. It did happen to me a couple times, and I put a 'G' kit in my 92FS to 'solve' the problem. Now, if I swipe it, I've just decocked the gun and have a DA pull - but it goes bang. There are some S&W's that have this style safety, and of course Walther P38's, PPKs, etc. But I don't own any of those that I'd ever intend to use for defensive purposes, so I'll put up with it.