I hear ya. You might be right, there may not be much to be concerned with in the way of changes. But I do know this, that sometimes a bit of barrel makes a huge difference in velocity and performance of a bullet. With AR's I've seen it said that sometimes there are greater increases at different points in a barrel. And I'll just show the 110 +p buffalo bore chart to make that example. There is a HUGE difference between the 4" and 6". But like you say, it's probably moreso because velocity is already high on it. I just don't want to assume what load might do better. But there may be no other way of knowing...... Cuz I just don't see many 6" tests.
1438 fps -- Ruger GP 100, 6 inch barrel
1287 fps -- S&W Model 15, 4 inch barrel
1210 fps -- S&W Model 66, 3 inch barrel
1202 fps -- Ruger SP101, 3 inch barrel
1149 fps -- S&W Model 66, 2.5 inch barrel
1119 fps -- S&W Model 60, 2 inch barrel
1104 fps -- S&W Model 340, 2 inch barrel