this business sells supplies to small businesses. Currently using sage to handle POs, Sales orders, invoices and bookkeeping. Using sage to handle one order you have to go into 3 different screens/modules just to handle an order and an additional two if it needs to be drop shipped. Is there a software or app that streamlines this process?

Employees.

Seriously though, we use QBO (which kind of stinks) to manage kind of a lot of inventory (specifically the purchasing and receiving - NOT the handling of individual customer orders - that's custom, inhouse software). We've looked at a lot of other options. They all have pros and cons... and we are still with QBO.

It takes employees to make it run smoothly. That's the hack with business software.