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MTM is the way to go.
Cost will be primarily dictated by your choice of fabric.
Learn the difference between "bespoke" and "made to measure" as the two terms are NOT interchangable.
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This.
I have a similar daily dress to what you describe. When I changed positions in company I had nothing really (a pair of pants and a sportcoat) after wearing scrubs to work everyday for 20 yrs, at least in terms of office attire. Brooks Brothers is still GTG for ready to wear and of course their shirts are great.
I think another consideration is how hard is it for you to find clothes that really fit. Unless you fit pretty normal dimensions for standard off the rack clothes MTM may be a better option.
Bespoke sounds great but is the $$$$ worth it for you? I know for me off the rack stuff does not fit worth a darn. Short, stocky and pretty thick chest and shoulders I'm much better off with something made to my measurements. Plus since discovering I like dressing better I like stuff like functional buttons on jacket sleeves, french cuffs and shirts that fit my neck without choking me, but are not like wearing a tent around your body.
So your body, how clothes fit you and your overall style is a good guide to which way you may want to go. Lots more options with MTM.