Assuming you might keep a pistol for other than plinking tin cans on a lazy afternoon. Lets say that you might need to save a life with it some day, then the gun you shoot best is the one you will want to have in your hand if and when that time comes. Get the gun that fits you best and you shoot best.
Having said that a few observations. To paraphrase the venerable Jeff Cooper; a double action trigger on an autoloading pistol is a solution in search of a problem. The autoloader with a DA trigger is essentially the product of a bureaucrat's mandate due to fear of wrongfull death lawsuits. Bureaucrats are unwilling to mandate, and more importantly fund, sufficient training and practice to allow people they requrie to carry a pistol to be truly proficient. Effectively, the DA trigger on an autoloader is a bureaucrat tapping you on the shoulder in that gut wrenching moment when you whip out your pistola to save your life and asking "Hey buddy, do you really mean to pull that trigger?". The long, and usually hard, DA trigger pull kills accuracy in small handed/weak trainees, so an improvement in accuracy can be gained by going to the Glock trigger. As the trigger pull gets easier the number of accidents go up.
Now I have to be honest, I don't like Glocks because they don't have a safety. They do have some excellent design features. The axis of the barrel is low, close to the axis of support (forearm) yielding good recoil characteristics. But, it still don't have a safety, and nothing I can say is as damning as the fact that there is an aftermarket for a piece of plastic you jam behind the trigger and push out with your trigger finger when "you really mean to pull that trigger".
As for the safety on a 1911 design slowing the first shot, well just last month at the Steel Shoot up in Weld County, CO one course of fire was an 18 in wide 24 in tall plate with a 10 in circular stop plate above it on a single post at 10 yards. At the beep you had to draw, disengage the safty (on pistols with them) and put 4 hits on the big rectangle and one on the stop plate. Now I'm just a middle of the pack competitor, the best I could do was a bit under 4 seconds. The fast guys, yes using 1911 designs, could do it in under 1.9 seconds. Yes that is draw, safety, and 5 aimed rounds in under 2 seconds, and they did it consistantly with iron sights.
Perfect practice is the key. As a top notch competitor once told me; "Don't worry about the guy that spends $1000 on his gun, worry about the guy that spends $1000 on primers." If you aren't practicing enough to make operation of simple controls on the pistol second nature then you ought not to be relying on it to save your life, or the life of a loved one.
Another point regarding a lack of a safety on the Glock. Do you have kids? Is the gun ever loaded when it is not in your direct control? Would it ever be possible for a bad guy to get control of your gun? If the BG takes a moment to fumble with a safety, it could be your chance to take corrective action.
Good luck with whatever you decide, and please practice with what ever you have.