What caliber will you be using?
You need to zero in the old "black powder" rifle cartridge repeaters, modern pistol cartridges and even the 30-30 at the distance you will be shooting at the most. These cartridges have a bit more trajectory than "modern" cartridges like the 30-06, 243, 270 of which the POA at 50 yards is basically the same at 200 yards.
It is ideal to zero the scope in at the greatest distance you plan to shoot since the target will be it's "smallest" and harder to hit with having to add windage and elevation corrections.
Here is what my target board looks like for the 44-40 with the range POA's added from 25 yards to 265 yards. 265 yard POA would be 9 3/4", just above the target board.
"Flip" the POA for each range and that gives you the bullet's trajectory. Notice the "apex" is 100 yards, "bullet drop" starts past 200 yards with this particular zeroed in range.
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