I haven't played with universal but I have with unique. you can throw 5gr in almost any pistol cartridge and it will work pretty well (aside from the really small and large) toss in 8-10gr in most rifle cartridges with a cast bullet and you have a fun plinker. I've used unique in 9mm, 38/357, 40, 45, 45LC, 30-30, .223, .308, 45-70 and 12g just to name a few off the top of my head. is it the best at all of those? nope but does it go bang and work good enough for plinking...you bet. if you cast unique is a great powder to have on hand for a do-all.
Like dryflash mentioned that and H4895 would be good enough for most applications. will it yield top performance? not likely except cartridges ideal for them. H4895 also has a lot of youth load data which can make those pesky magnums turn into tame animals. Hodgdon did an article on MEL's (managed effective loads) and that was one of the top powders for making some of the bigger safari grade cartidges manageable for normal hunting.