Lovely rifle, OP. Of course, I may be biased:
It is absolutely the last rifle I'd ever sell.
Mine is in .44-40. Pic taken while deer hunting. (Haven't connected with a deer yet, but came this >< close last year to getting a good shot.)
I mostly shoot BP handloads in Starline brass.
Anyway, a couple tips based on experience with my rifle:
You should remove the side plates and Loctite the little screw that secures the loading gate to the right sideplate. Mine loosened a little eventually and backed out enough to interfere with the toggles, causing the rifle to jam.
However, before removing the side plates soak the screws for a couple days with a good penetrating oil, and use properly fitting, hollow-ground gunsmith's screwdrivers. Uberti's assemblers love to really crank down on the screws, and the heads are not properly hardened. I bought a set of properly hardened screws from VTI Gun Parts for my rifle.
Finally, if you handload be advised that they are sensitive to cartridge OAL. Too short or too long and the action will bind or even jam. If your rounds are in spec, though, it will be very reliable and smooth, and after you get it apart for the first time, very easy to maintain.