Things to consider for the OP.
#1 You can only ship Ammo UPS or Fedex NO USPS! Ammo is heavy! Till you have volume shipments UPS and FEDEX are not going to be offering you better rates.
#2 Buy enough powder to sell online you would need to be a different league! Buying powder buy the truck load direct from Alliant, Hodgdon, Western, and Capstone.
Then you get into the storage of powder and primers. Plus you need to have an account with FEDEX or UPS plus the Haz Mat Training! Then add the Haz Mat tag cost to the order and well between the shipping costs and HazMat Fee that the consumer would be paying they have to order enough powder to make it cost effective.
#3 Many of the big boys require FFL, Store Front, and other issues.
#4 Inventory at low prices COSTS MONEY and again warehouse area.
And, places like Olin - Vista Outdoors (Federal, CCI, Speer) they like contracts! Same as Hornady. And, min spend to get in the door is ranges from 100 to 500K
There is no way to make money buying powder and primers from large wholesalers because you would have to compete with places like Powder Valley.
Unless the powder come on a pallet on commercial truck the limit is 100# of powder. And, UPS and FEDEX is 50# limit per carton
Then there is collecting sales tax on shipments at least to 4 states OR WA PA and MN let alone your own states