If you are talking about Speer's 130gr varmint bullet, I think they may be greatest thing since sliced bread. I say may, since I have yet to shoot a deer with them, just developed a load in my pistol this year.
I played with 3 powders, IMR 4227, Vihta N110, and accurate 11FS. With all 3 powders, and any load or OAL I tried, they were just plain stupid accurate. In gallon water jugs they mushroom beautifully
anywhere from mid 1400's impact up to near 2000 fps. I have difficulty shooting an ar pistol all that well, and I can shoot these into under .5" center to center at 55 yards, the only two groups I shot at 110 yards
were 5 shot groups I shot on two different days. The biggest of those two was just under 1.2 ", the other one was probably one of those fluke groups you will never see again and I don't count it. 4227 was only good
for mid 1800 fps out of my 9" pistol, N110 was high end of mid 1900's, and the load I'm using with 11FS is about 2010 fps. I use starline brass which has a lower case capacity than anything else. From testing,
I think if I stuck with the N110 and messed more with OAL it would have been slightly more accurate than 11FS. The reason I didn't keep working with N110 is my supply is low and I have other cartridges I use it in.
Instead of the 250 ogive method Dryflash suggests, I just use a modified magazine that works with blackout no matter what, probably wouldn't work in my .223's and I don't care.