Think of it this way, if the .17 had problems, this new round will have more. Why? More of the things that limit the use of the .17 in a blow-back design to begin with. The high pressure curve, the fact that .17's need a really clean chamber to work right, etc. Now as for DI, well while it sounds nice this is still a rim fire that by center-fire standards is a small cartridge. We are not talking about a big volume of gas here.
Rim fires have their limits, its why we have center-fires. While this new round has a nice nitch to fill and I believe it will be very popular, as I see things it belongs in a bolt or lever gun. Do some research on how many issues people have trying to make the current .17 rimfires work in semi-autos. Now add even more power to that equation and the problems rise accordingly.