I have three leverguns in magnum-handgun calibers, along with several single-shots in the same calibers. The three leverguns are all Puma/Rossi's - top to bottom are 20" .454 Casull, 16" .44 magnum, and 16" .357 magnum:
My most-used and 'favorite' one is the .357, largely because it's so compact yet capable. In addition to the scout mount and red dot, it's had its barrel threaded & magazine tube shortened to allow use of my abraxas suppressor.
It'll run 140's up to right at 2,000fps and 125's slightly faster. Basically, it's the size of a standard 10-22 and the power of a .44 magnum revolver. The gun also pushes subsonic 158's thru the suppressor quieter than my GAMO 177 pellet gun. (I don't load bullets heavier than 158's in it due to the slow rifling twist.)
While not my 'favorite', the .454 is the most versatile of the three, running anything from light bunny-fart LC loads up to full-house .454's which put out more muzzle energy than a lot of .30-06 loads have.
The .44 is a great gun but pretty much never gets used. It's kind of like a 16-gauge shotgun to me. There's not a thing wrong with it and it's absolutely capable of doing pretty much anything I want or need to do, but I simply never use it; always go down to the .357 or up to the .454 instead. It's more than a decade old and probably doesn't have 500 rounds thru it.