I use lee, rcbs, lyman & hornady dies to reload the different pistol calibers I reload for (9mm/38spl/357/44spl/44mag/45acp). I don't worry about bullet runout in the revolver/roll crimp loads. Never saw it very more than 10/1000th's. Taper crimped semi-auto's on the other hand are a whole different animal. If my loads for a semi-auto pistol have over 5/1000ths runout, I'm doing something wrong. Why the concern??
Things like jaming the bullet into the lands and bullet setback & short start pressure come into play. Paranoid?? Perhaps. But it's better to be safe than sorry.
Most reloaders look at this picture and they see the work "accuracy" and set their loads up just like the picture above, flush with the hood of the bbl. I always set my semi-auto's up to look like the normal picture and I measure my loads targeting them to sit 20/1000th's below the hood of the bbl. That 20/100th's buys me room for bullet runout, fouling that builds up & keeps an even short start pressure which to me is more important for accuracy then where the bullet starts.
At the end of the day your concerns about bullet runout depends on how you set your loads up to start with. If you were smart and set them up so they were 10/1000th's to 20/100th's below the hood. Then you have a built in safety factor in place and your runout won't affect anything. If you set your loads up at the raggedy edge of max, then ya runout comes into play. You never said how much runout, allot of runout to me is anything over 5/1000th's.
Something to think about:
Most reloaders do the "plunk" test to make loads. They never do the "plunk" test when it's most important, namely after a range session. Especially with cast bullets!!! Junk builds up in the throat of the chambers and that buildup is measurable. I use a dummy round to measure the buildup testing the bbl at the 100round count, 200 round count & 300 round count. I also take my bullet runout into consideration. The end result is I have an idea how many rounds I can shoot before my reloading habits and fouls affect the accuracy and safety of myself and the firearm being used.
Anal??? ya!!! But at the end of the day if the reloads were setup for "max" accuracy/flush and I had 20/1000th's runout and 15/1000th's buildup in the throat of my bbl for a long range session I just greatly increased my odd of bad things happening. Add to that the use a a powder that's know for it's extremely high short start pressure, the odds just went up again. So ya, you could easily be slamming 35/1000th's of that bullet into a hole smaller than it's diameter causing pressure spikes. Or worse yet cause bullet setback.
Be safe, setup your loads so they have a built in safety margin. Have an idea of how the fouling buildup affects your oal's and keep an eye on the bullet runout.