So you're asking how to zero an optic and adjustable iron sights then, not how to operate this particular optic, because that page gives you everything you need.
Start at 25 yards. Have a buddy with you. Shoot 3 shots aiming at a bullseye. If the 3 make a group, aim at the bullseye again and make sure you don't let the rifle move at all. Have your friend dial in windage and elevation until your crosshairs are on the group. But you can't let the rifle move while they do so. Shoot another group of 3 and it should be pretty close. Assuming it is, move out to your chosen zero distance and verify. Fine tune windage and elevation. Then adjust the irons to match. Or you could choose a different zero, perhaps more CQT distance so you don't have to worry about holdover. Up to you.
Once you get your zero, you might want to make witness marks. Then you can play with the dials and always get back to zero. I'd assume 1 click=1/4" at 100 yards.