My friend has a full size 45.
I never shot it but he says it is very pleasant to shoot, accurate (he's not a very good shot), no stoppages in the probably 250 rds through it.
Major problem, he managed to assemble it wrong and locked the slide up with the takedown pin fully inserted. Can't rack the slide, can't move the lever. He sent it back on ruger's dime. We'll see what happens with it. Obviously this isn't much fault of the product, but the user being stupid.
I didn't get to play with it for more than a minute before I had to go, so maybe the problem is fixable by an experienced user. In that minute I also wasn't trying to force anything more than I could do with my own hands.
To me the grip felt nice and ergonomic, seemed of very high quality for its price range.