I put off getting a PPQ for a while. Got a second P228, an SP2022 and the VP9 before coming across a deal on a PPQ I couldn't pass on. After shooting it the first time, I was kinda kicking myself for not getting one earlier.
I have had some issues with mine, but I have not attributed them to the pistol itself. First, I had the slide seize up just out of battery on a live round. And I mean seized up. No power stroking, not even putting my body weight on it with the nose of the slide against the bench. Had to work on it at home with a covered punch and mallet. I don't blame the pistol, as they were reloads from a previously trustworthy source. They were a bit hourglass shaped. They all worked fine in my SIGs, but apparently the PPQ has a stepped chamber that said no-go.
The second issue was two stovepipes and a near squib, all consecutive. That turned out to be a bad lot of factory ammo, which the manufacturer replaced.
Most recently, I took the PPQ out on a chilly, windy day. Was going to do a sight swap and wanted to get before and after groups to see if elevation changed much (windage is obviously easily adjustable on the PPQ). Well, I went to shoot my first string of 15 and immediately got "click" on the trigger pull. Chamber check, yup it's loaded. That should've been enough to recock so let's try again. Click. Drop the mag, eject the round, inspect the case. Light primer strike. 5 rounds in a row before I went back to the bench. Took those 5 and they went off no problem in the VP9. Tore the PPQ down and pulled the striker. Grease. Why is there grease on my striker/in the striker channel?? Wiped it down and reassembled and started getting ignition. Did a good cleaning that night and the pencil test damn near put a hole in my ceiling. I did buy the pistol used (the guy literally had it 4 days) and he had used froglube on it. Based on that decision, I wouldn't be surprised if he was challenged enough to think lubing the striker was a good idea, but it wasn't froglube in there (at least it didn't smell like mint). As specific as Walther is about where to lube and how much, I doubt it was factory lube. I also seriously doubt the dabs of grease I put on the rails migrated into the striker channel.
Anyway, even though I don't attribute any of the failures to the pistol, they all were serious failures that rendered the pistol inoperable. It will be a good number of rounds fired through it before it gets carried again.
As for my set-up, I have big hands so I run the large backstrap. Also gave the Talon rubberized grips a try and I like them. Wish they actually added more girth to the grip. And I did manage to get the sights swapped to Mepro 18801s. It shifted POI slightly higher, but nothing I take issue with.