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what should I look for and any issues? thanks...
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Other than the obvious cracked or broken parts, check the slide to frame rail fit. A little movement is fine, but if you can hear it rattle when shaken, that's not a good sign. Also check the frame rails. There should be no chips or gouges. Look down the barrel with a light checking for rust, nicks or scrapes.
That's about it. It's a good idea to put a spring kit in if you don't know that last time they were changed. Not sure there is an actual kit for the p225, but change the decocking lever spring, slide catch lever spring, trigger bar spring, recoil spring, and the slide pins (the ones that hold the breach block in) and if it were me I'd change the firing pin spring since I had the breach block out and it's inexpensive.