Just my $.02 but if reliability is your #1 concern, I'd stick with a Colt mag based system. The design (and the parts available for it) have been around a lot longer so its just a more proven system.
The other key IMO is don't buy parts based on price. Buy based on proven track record, even if that means spending more $. it's fine to try and save money if you are willing to tweak parts for a range toy but its not a good idea to do that for something you may need to use to save you or your family's life and with that in mind, there is a strong argument to make for just buying a factory built Colt 6951 and be done with it.
But if you want to build something up yourself, stick with well known parts with a strong history of quality and functionality.
For instance, I went with a Hahn magwell adaptor and Metalform mags which is probably the most expensive combo out there but it works with no tweaking, tuning or anything else. Rarely do you hear about anyone having issues with either of those items and I don't know that I've ever heard of someone having issues when using both together? (Although this is ARFCOM so now that I write that, some one will come out and claim they did
)
I also went with a ramped bolt (RRA) and rounded M16 style hammer (LMT) and a Colt 9mm buffer with Sprinco "red" x-power spring and NFA spacer.