Per loading doctrine you DON'T shove a mag in unless the bolt is back, regardless. It requires you to compress the bullet stack against the heavily loaded mag spring, it might fit with friction spreading the mag body but can fall out if the mag catch isn't fully engaged. In other words, bad practice. Always retract the bolt.
Some say there is a tactical application where you reload to a full mag while still needing a round in the chamber, fine, your SWAT/SERT Team policy as enforced by your instructor will apply. Meaning that you likely will never need to do that shooting dirt on a public range. Swip swapping partially loaded mags is something for tactical experts which there are actually very few.
As for the .300 BO using "all 5.56" parts Magpul disagrees - and just offered a .300 specific mag. Why? Because the width of the bullet stack just forward of the cannelure is larger with the bigger .300 bullets compared to .223, and that means they rub the front rib and cause friction, including jams and stoppages. Since there is a real danger of mixing rounds in guns, having a .300 specific mag marked for that use is a necessary safety measure. It will also help feeding as some have noted, 5.56 mags are not optimal and will cause issues. We knew this all along but the popular myth about "same as 5.56" is so spread around it's reached mythological proportions.
So, Magpul has the final say, and those are the only .300 BO mags on the market now. Everything else is taking a chance.