Quoted:
I've never thought I needed the anti rotation pins but I'm starting to doubt that. My last pistol build using an Anderson lower and an extra Colt trigger and hammer, I can watch the hammer pin rotate when I pull the trigger to dry fire the gun. Will this case any wear to the lower or is it an issue at all.
Btw, the pin is turning almost half a turn on each trigger pull.
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I'd say your estimate is high, since the hammer goes through less than a quarter turn during each cycle.
If it moves it will cause wear. But the wear is insignificant in comparison to the lifetime of the lower, unless the lower is itself defective.
An extra Anderson lower is probably cheaper than a set of anti rotation pins, and the likelihood you'll notice wear from the rotation in your natural lifetime is pretty low.