1. No-they are all over the map when it comes to compatibility.
2. It's very easy to use a rifle length handguard with a 16" barrel, unless you have a Front Sight Base on the barrel. Most people install a low profile gas block under a free float handguard. This would be ideal for your application.
3. Barrels can be changed with relative ease on the AR10, but not in the field, unless you have a complete separate upper, or a quick change barrel system. Many people have dealt with increased performance by shooting more aerodynamic bullets, as opposed to looking for longer barrels.
4. Almost all the AR10 configurations out there support rear iron sights, as well as optics. Front sights are another story, but will be fine if you use a 12" handguard with a top rail, and mount your front sight there. Very few people use iron sights on AR10's, since there are so many affordable optics that are also rugged.
5. There are detachable sight housings, commonly called the "carrying handle", even though that design originates from the first AR10's, which had a trigger style charge handle in that area.
6. Yes. You can use most of the AR15 telescoping stocks on the market.
7. Sling is easy
8. There are almost endless flash hider combos.
9. You need to carefully select AR10 appropriate buffer and spring combos, with one of 3 different tube lengths.
* AR15 carbine tube/AR10 carbine buffer & spring
* ArmaLite/Vltor A5 tube/AR15 carbine length buffer (heavier) & AR10 spring
* AR15 rifle tube/AR10 rifle buffer and spring
10. There are tons of trigger options. A good hunting trigger can be found that will fit your likes.