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Posted: 11/9/2008 5:38:46 AM EST
[Last Edit: 11/25/2016 11:23:07 PM EST by gaspain]
What is protein folding and how is folding linked to disease?
Proteins are biology's workhorses –– its "nanomachines." Before proteins can carry out these important functions, they assemble themselves, or "fold." The process of protein folding, while critical and fundamental to virtually all of biology, in many ways remains a mystery.

Moreover, when proteins do not fold correctly (i.e. "misfold"), there can be serious consequences, including many well known diseases, such as Alzheimer's, Mad Cow (BSE), CJD, ALS, Huntington's, Parkinson's disease, and many Cancers and cancer-related syndromes.

You can help by simply running a piece of software.
Folding@home is a distributed computing project –– people from throughout the world download and run software to band together to make one of the largest supercomputers in the world. Every computer takes the project closer to our goals. Folding@home uses novel computational methods coupled to distributed computing, to simulate problems millions of times more challenging than previously achieved. "

Our team stats page, click here.
-------------------------------------------------------------------------------

Install Guide:

Download client, click here:

upon install:
  1. enter in team 40965
  2. Enter your arfcom nick name.
  3. Program will finish install.
  4. On your desktop the program is called FAHControl. Run this.
  5. It will download a "work unit" and the start processing it, you will notice your PC fans kick on.
  6. its all automatic from here, just let it run as long as you can. If you need to pause there is a control button on the taskbar, looks like multicolored blobs. Right click to show controls.
another install guide is here.
-------------------------------------------------------------------------------

Some things to know:
  • This will make use of 100% of your processor and GPU. You may experience a higher electrical bill, and wear and tear on your PC due to heat, so make sure your fans are clean and working.
  • How many PPD (points per day) can I expect from my PC with what GPU? est. (you can also double or triple these numbers with SLI or Crossfire)(some older ATI cards show low numbers, they were not optimized for folding and use more power)
    • 800 ppd, ATI 4650
    • 2000 ppd, Nvidia GT220
    • 5,000 ppd, Nvidia 8800GT
    • 5,000 ppd, Nvidia 9800GT
    • 6000 ppd, ATI 5870m laptop
    • 7800 ppd, Nvidia GTS 450
    • 8000 ppd, Nvidia GTX 285
    • 12,000 ppd, Nvidia GTX 450
    • 12,500 ppd, Nvidia GTX 560
    • 15,000 ppd, Nvidia GTX 295
    • 18,000 ppd, Nvidia GTX 570
    • 20,000 ppd, Nvidia GTX 580
    • 27,000 ppd, Nvidia GTX 590
    • 28,000 ppd, Nvidia GTX 660
    • 37,000 ppd, Nvidia GTX 660Ti
    • 37,000 ppd, Nvidia GTX 670
    • 44,000 ppd, Nvidia GTX 680
    • 80,000 ppd AMD R9 270
    • 120-180,000 ppd AMD R9 280
    • 180,000 ppd AMD R9 290
    • 150,000 ppd, Nvidia GTX 780
    • 190,000 ppd AMD R9 380
    • 250,000 ppd AMD R9 280X
    • 300,000-500,000 ppd, Nvidia GTX 980
    • 320,000 ppd AMD RX480
    • 350,000 ppd, Nvidia GTX 1060
    • 650,000 ppd, Nvidia GTX 1070
    • 700,000 ppd, Nvidia GTX 1080
Link Posted: 12/18/2008 9:15:02 AM EST
Joined we need more folders.
Link Posted: 12/18/2008 9:52:22 AM EST
[Last Edit: 12/18/2008 9:58:01 AM EST by ZekeMenuar]


OOPS! Double tap. Getting more coffee to compensate.

Link Posted: 12/18/2008 9:53:34 AM EST
[Last Edit: 12/18/2008 11:12:00 AM EST by ZekeMenuar]
Originally Posted By StewartTR:
Joined we need more folders.


More info please. I have two desktops sitting idle.
One fairly decent box. One old horse and buggy PIII. Both running W2K

Assigned two desktops to it. One pretty good Dell and one ancient HP.

ZM

Link Posted: 12/18/2008 11:31:56 AM EST
crap, already joined Ubuntu fah group...

I also stopped my program from running...using alot of cpu on a P4...not sure how much P4s can take. I dont want this one going down.

Anyone care to share info on how much processors can take?
Link Posted: 12/18/2008 11:34:11 AM EST
I'm already there.
Link Posted: 12/18/2008 11:36:37 AM EST
Originally Posted By Headlice:
crap, already joined Ubuntu fah group...

I also stopped my program from running...using alot of cpu on a P4...not sure how much P4s can take. I dont want this one going down.

Anyone care to share info on how much processors can take?


they can go 24-7, actually its beneficial to them to remain at a constant temperature. Less constricting and expanding.

But a P4 will eat your electric bill up pretty quickly.

If you have a newer Nvidia graphics card you can run folding on it and it blows CPUs and PS3's out of the water.
Link Posted: 12/18/2008 11:37:23 AM EST
In.

Crunching with my Nvidia 280GTX.
Link Posted: 12/18/2008 11:45:28 AM EST
Joined on one of my work machines. I could probably get another 30 servers running over the holidays, but then I'd have to clean them up before we come back January. But I'll see what I can do.
Link Posted: 12/18/2008 12:30:58 PM EST
on on my ps3.
Link Posted: 12/18/2008 1:12:37 PM EST
I assume I will show up on the team page when my PC starts turning in WU's?
Link Posted: 12/18/2008 1:17:21 PM EST
The CPU client runs at a very low priority. Even though you cpu usage shows near 100% you won't notice much slow down as the client gives up it's time for higher priority programs.

The GPU client is the most productive if you have a newer kick but video card you should look into it.
Link Posted: 12/18/2008 1:18:04 PM EST
Originally Posted By schizrade:
I assume I will show up on the team page when my PC starts turning in WU's?


Yes I could be a while before you turn in a work unit depending on how fast your PC is.

Link Posted: 12/18/2008 1:40:30 PM EST
[Last Edit: 12/18/2008 1:43:15 PM EST by schizrade]
Originally Posted By StewartTR:
Originally Posted By schizrade:
I assume I will show up on the team page when my PC starts turning in WU's?


Yes I could be a while before you turn in a work unit depending on how fast your PC is.



Already dropped one, Time to check.

Hmmm, noting yet, they probably recalculate every day.
Link Posted: 12/18/2008 6:33:14 PM EST
Sweet, 3 done.
Team Rank 76.
Link Posted: 12/18/2008 7:20:06 PM EST
Good work guys!

Arfcom rules! Team Ranking (incl. aggregate) 506 of 150021
Link Posted: 12/18/2008 8:12:26 PM EST
[Last Edit: 12/18/2008 8:21:05 PM EST by SplatSTi]
Downloaded and Joined, processing now.
Link Posted: 12/18/2008 8:13:52 PM EST
Originally Posted By SplatSTi:
Ok im a tard, what do I download?


http://folding.stanford.edu/English/Download
Link Posted: 12/18/2008 8:21:23 PM EST
[Last Edit: 12/18/2008 8:22:45 PM EST by SplatSTi]
Originally Posted By gaspain:
Originally Posted By SplatSTi:
Ok im a tard, what do I download?


http://folding.stanford.edu/English/Download


I might as well put this dual core to work, I should load it up on a few more machines too.
Link Posted: 12/19/2008 5:59:31 AM EST
[Last Edit: 12/19/2008 6:00:03 AM EST by StewartTR]
Yes! I have one machine running 2 GPU clients, 1 CPU client and 1 SMP client.

My other machine is running 1 GPU client, 1 CPU client and 1 SMP client. I have also put it on a couple machines at work.

I'm thinking about adding a nother 4850 to my secnd machine and running two GPU clients on it as well.
Link Posted: 12/19/2008 11:33:19 AM EST
Wow, this GPU client is fast on my 280GTX. I am cranking out 1 WU every 1.5-2 hours.
Link Posted: 12/19/2008 11:51:27 AM EST

My Dell, 2.2ghz Celeron, 1GB RAM W2K, will be finished at about noon Saturday.

The ancient HP, 1ghz PIII, 256mb RAM W2K, will be finished on Dec 31. This isn't the fastest computer on the block, but it's stable and reliable.
Link Posted: 12/19/2008 3:03:01 PM EST
This may sound like a dumb question... but is the folding at home project producing measurable results?

If not, do they know what kind of time-frame to expect some results?

Or does it not work like that?
Link Posted: 12/19/2008 3:05:57 PM EST
It has already returned results. I will try to dig up some links and post them.
Link Posted: 12/19/2008 3:07:03 PM EST
Link Posted: 12/19/2008 4:34:43 PM EST
Stickie FTW!
Link Posted: 12/19/2008 4:39:33 PM EST
Originally Posted By schizrade:
Wow, this GPU client is fast on my 280GTX. I am cranking out 1 WU every 1.5-2 hours.


damn that is fast! My PS3 would only crank one out every 8 hours
Link Posted: 12/19/2008 6:47:57 PM EST
Originally Posted By gaspain:
Originally Posted By schizrade:
Wow, this GPU client is fast on my 280GTX. I am cranking out 1 WU every 1.5-2 hours.


damn that is fast! My PS3 would only crank one out every 8 hours


CUDA is the hot new API. I do CUDA work and I can hardly believe how fast it is at times. I remember doing fast 4 hour SETI units years ago.
Link Posted: 12/19/2008 10:59:05 PM EST
How do I do GPU units? I am doing CPU units and they are crunching away nicely.

Score: 79 SplatSTi 749 1

Link Posted: 12/19/2008 11:26:13 PM EST
I must be doing it wrong, I'm not showing up on the team status page thing.
Link Posted: 12/19/2008 11:33:51 PM EST
Originally Posted By Wyzardd:
I must be doing it wrong, I'm not showing up on the team status page thing.


It takes a couple days
Link Posted: 12/19/2008 11:36:33 PM EST
Originally Posted By SplatSTi:
How do I do GPU units? I am doing CPU units and they are crunching away nicely.

Score: 79 SplatSTi 749 1



you need a CUDA compatible gpu. Thats about all I know...because I dont have a CUDA gpu either
Link Posted: 12/20/2008 10:02:21 AM EST
[Last Edit: 12/20/2008 10:37:54 AM EST by SplatSTi]
Originally Posted By gaspain:
Originally Posted By SplatSTi:
How do I do GPU units? I am doing CPU units and they are crunching away nicely.

Score: 79 SplatSTi 749 1



you need a CUDA compatible gpu. Thats about all I know...because I dont have a CUDA gpu either


I have an ATi HD 4800 series video card. 512mg ram 1.2 teraFLOPS, would have figured that would do the job.

Edit: ah ha!! Figured it out. Need to download the GPU client.

http://folding.stanford.edu/English/DownloadWinOther
Link Posted: 12/20/2008 3:31:31 PM EST
Originally Posted By gaspain:
Originally Posted By Wyzardd:
I must be doing it wrong, I'm not showing up on the team status page thing.


It takes a couple days


Ah, it's showing now. Thanks.

88 Wyzardd4arfcom 238 2
Link Posted: 12/21/2008 3:11:39 PM EST
uh how big are these work units? my gpu one is doing 10,000 at a time. When I first started I was using the CPU one at the first one was 500, now its like 2500. Obviously it takes alot longer to do 10,000 at a time.

What sizes are you guys dealing with?
Link Posted: 12/21/2008 3:19:28 PM EST
Just joined.
Link Posted: 12/21/2008 11:24:22 PM EST
My passive-aggressive competitive nature is rearing its ugly head. When I get into work tomorrow I'm loading it up on some more machines. I'll have to unload after the first of the year, and I'll never reach the top 10, but it's going to be slow at work anyway.

79 Wyzardd4arfcom 1212 4
Link Posted: 12/24/2008 9:21:59 AM EST
Originally Posted By SplatSTi:
uh how big are these work units? my gpu one is doing 10,000 at a time. When I first started I was using the CPU one at the first one was 500, now its like 2500. Obviously it takes alot longer to do 10,000 at a time.

What sizes are you guys dealing with?


The system assigns you WU's as they come. Most of mine are 15,000,000 in size. You get more points on size/time to complete. Compared to most you are flying through them. Hell I have been doing it for about a week and I have moved up to #30 in the team rankings. I can crank out a large WU on my GPU in about 1.5-2 hours. My Core i7 OTOH takes over 8-12 to do a large WU.
Link Posted: 12/24/2008 12:23:55 PM EST
Originally Posted By schizrade:
Originally Posted By SplatSTi:
uh how big are these work units? my gpu one is doing 10,000 at a time. When I first started I was using the CPU one at the first one was 500, now its like 2500. Obviously it takes alot longer to do 10,000 at a time.

What sizes are you guys dealing with?


The system assigns you WU's as they come. Most of mine are 15,000,000 in size. You get more points on size/time to complete. Compared to most you are flying through them. Hell I have been doing it for about a week and I have moved up to #30 in the team rankings. I can crank out a large WU on my GPU in about 1.5-2 hours. My Core i7 OTOH takes over 8-12 to do a large WU.


Yeah, It almost has me wondering what would happen if I got another video card and put the joined them if it would go any faster, this video card is surprising me, I stopped running the CPU and I'm only running the GPU. I know this isn't a race, but damn, its beginning to feel like one, competitive spirit is coming out.
Link Posted: 12/25/2008 6:59:16 AM EST
[Last Edit: 12/25/2008 5:28:32 PM EST by StewartTR]
Originally Posted By SplatSTi:
Originally Posted By schizrade:
Originally Posted By SplatSTi:
uh how big are these work units? my gpu one is doing 10,000 at a time. When I first started I was using the CPU one at the first one was 500, now its like 2500. Obviously it takes alot longer to do 10,000 at a time.

What sizes are you guys dealing with?


The system assigns you WU's as they come. Most of mine are 15,000,000 in size. You get more points on size/time to complete. Compared to most you are flying through them. Hell I have been doing it for about a week and I have moved up to #30 in the team rankings. I can crank out a large WU on my GPU in about 1.5-2 hours. My Core i7 OTOH takes over 8-12 to do a large WU.


Yeah, It almost has me wondering what would happen if I got another video card and put the joined them if it would go any faster, this video card is surprising me, I stopped running the CPU and I'm only running the GPU. I know this isn't a race, but damn, its beginning to feel like one, competitive spirit is coming out.


No but you could get a second video card and run two GPU clients one on each card. It takes some doing to get it working though.


http://folding.stanford.edu/English/WinGPUGuide#ntoc4
Link Posted: 12/27/2008 5:07:46 PM EST
I'm in!
Link Posted: 12/29/2008 2:09:42 PM EST
Just got a GTX 280 setup and folding. Dam that thing screams!
Link Posted: 12/29/2008 2:36:06 PM EST
I have go for quantity over quality. Most of my servers are optimized to do little more than push fibre channel I/O, and they've been down for a week. If my IT department would get on the ball and fix the PDU's I might be able to get something done.

As it is, I've moved up to 42nd. Not bad for a laptop and a couple desktops I guess.
Link Posted: 12/30/2008 10:24:54 AM EST
Originally Posted By Wyzardd:
I have go for quantity over quality. Most of my servers are optimized to do little more than push fibre channel I/O, and they've been down for a week. If my IT department would get on the ball and fix the PDU's I might be able to get something done.

As it is, I've moved up to 42nd. Not bad for a laptop and a couple desktops I guess.


I am just running my video card on my desktop, not even running the CPU one anymore.
Link Posted: 12/30/2008 9:17:03 PM EST
I'm in the process of moving all of my dual and quad core machines over to this team. Leaving the hostgator.com team for one more to my liking
Link Posted: 1/3/2009 10:18:49 AM EST
Originally Posted By SplatSTi:
Originally Posted By Wyzardd:
I have go for quantity over quality. Most of my servers are optimized to do little more than push fibre channel I/O, and they've been down for a week. If my IT department would get on the ball and fix the PDU's I might be able to get something done.

As it is, I've moved up to 42nd. Not bad for a laptop and a couple desktops I guess.


I am just running my video card on my desktop, not even running the CPU one anymore.


You almost caught me. The power went down on my 280GTX rig over about a week. Back up.

FEEL THE PAIN BITCHES!!!

Link Posted: 1/3/2009 11:59:38 AM EST
I'm going to have to unload most of the servers tomorrow, so I guess I'll wallow in mediocrity. If I can break into the 20's before then, I'll call it good.

33 Wyzardd4arfcom 28299 94
Link Posted: 1/6/2009 10:10:27 PM EST
Lost the sticky.
Link Posted: 1/6/2009 10:23:55 PM EST
Originally Posted By schizrade:
Originally Posted By SplatSTi:
Originally Posted By Wyzardd:
I have go for quantity over quality. Most of my servers are optimized to do little more than push fibre channel I/O, and they've been down for a week. If my IT department would get on the ball and fix the PDU's I might be able to get something done.

As it is, I've moved up to 42nd. Not bad for a laptop and a couple desktops I guess.


I am just running my video card on my desktop, not even running the CPU one anymore.


You almost caught me. The power went down on my 280GTX rig over about a week. Back up.

FEEL THE PAIN BITCHES!!!



Im still coming after you and Im only using one client. Dont make me boot up another machine just to do that
Link Posted: 1/7/2009 8:41:41 AM EST
Originally Posted By SplatSTi:
Originally Posted By schizrade:
Originally Posted By SplatSTi:
Originally Posted By Wyzardd:
I have go for quantity over quality. Most of my servers are optimized to do little more than push fibre channel I/O, and they've been down for a week. If my IT department would get on the ball and fix the PDU's I might be able to get something done.

As it is, I've moved up to 42nd. Not bad for a laptop and a couple desktops I guess.


I am just running my video card on my desktop, not even running the CPU one anymore.


You almost caught me. The power went down on my 280GTX rig over about a week. Back up.

FEEL THE PAIN BITCHES!!!



Im still coming after you and Im only using one client. Dont make me boot up another machine just to do that


What are you using?
Link Posted: 1/7/2009 9:30:06 AM EST
[Last Edit: 1/7/2009 9:31:25 AM EST by StewartTR]
GTX 280 is getting 8000+ PPD, taking a little over an hour for each work unit. That's about twice what I was getting with my ATI 4870 which was about 4000 PPD. I'm thinking about adding another GTX 280 and bring that machine up to 16000+ PPD.

By the way out team is moving up in the ranks. It was 507 when I started folding about a month ago. Now we are 488.

If the whole hive was in on this we would be #1 in a year! lol

http://fahmon.net/ <- cool program to monitor you folding rig and calc your PPD.
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