it's hard to improve on basic soft points in .30-06.
Fragile bullets like the nosler ballistic tip open hard and fast. Maximum expansion seems to be about 6-10" deep, literally liquefying a small melon sized volume of tissue at this depth. Deer frequently drop in their tracks, boom-flop. I'm running about 80-85% of kills dropping in their tracks, and the runners are only taking a dozen or so steps before dropping. Exit wounds are small, since most of the bullet is still in the deer (or so it seems). A dead on shoulder shot will be ugly. This is with a .308" diameter 165 at about 2620 fps. Drive it faster (as in a .30-06) and it will get really ugly and messy. It you want a dramatic explosive kill, these fragile rapid expanders are it. In a .30-06, I'd actually recommend a 180, since a bit slower won't be as messy.
Soft points (Fed/Win/Rem/Hornady interlocks) work really good. Not as explosive as the fragile ones, but reliable. You wont get as many boom-flop DRT kills, and your deer may well run 20-50 yards before piling up, but he's dead and just doesn't know it. And your meat won't be pre-shredded. Pick one: 150,165,180 by any of the big companies and your deer (or elk, or moose) is as good as in the freezer. This is the advantage of the .30-06. Its fast enough to open up very well, but not so fast that penetration is limited. And its got enough bullet diameter and mass that it drives a couple feet deep and works well. The .30-06 works very, very well with a basic no frills bullet.
Premium deep expanders like the Barnes TSX, Federal's Trophy Tipped Bonded or Trophy Copper, Swift's A-Frame, etc are designed to drive exceptionally deep. Expansion is less violent than with the Ballistic Tip clones or soft points, but penetration is enhanced. A deer is only 16" thick , so all this extra penetration is useless. In my experience, these bullets are great on moose but are actually LESS effective on deer. A large portion of the bullet's killing power is wasted on the 6" oak sapling and 30" of dirt on the other side of the deer. Deer are running 50,75,100 yards before piling up, and interior wound channels are less defined than with soft points. I use these on moose, but regular 150-165 softpoints actually kill faster and more dramatically than the expensive premium deep penetrators.
If you are shooting a little .243, I can see the advantage in a hard, premium bonded bullet. If the bullet starts out at 80 or 90 grains, you don't want to loose any of it. If you are shooting a slow-poke .300 savage, a fast expanding Nosler Ballistic tip works great. And if you are shooting a big magnum with impact speeds of 3000 FPS+, a controlled expansion, bonded bullet makes sense. However, the real magic of the .30-06 seems to be that it's already in a sweet-spot, and 108 years of bullet manufacturing experience have gone into designing and making bullets (regular soft points) that work very, very well the '06. Grab a box of Rem/Win/Fed 150/165/180 soft point regular non-premium ammo and your deer is as good as freezer wrapped.
Fro