@badredfish asked me for a topic on this so here it is. Feel free to discuss, talk about your own 22 Creeds, or ask questions.
I've been shooting and hunting with 22 Creed for a couple seasons. Started off as a Wildcat and recently obtained SAAMI approval. At a high level it offers slightly better than 22-250 performance, better geometry for feeding in a gas gun, and is more suited to long, heavy for caliber bullets than 22-250.
Pros:
Easy to load for (less than an hour of load development and I had a .33 MOA load for my current rifle)
Cheap to load
Wide bullet selection from ~40gr copper solids all the way up to 95gr AMAX
Cons:
Brass can be hard to find and making 22 Creed brass from 6mm Creed usually requires neck turning
Factory ammo can be hard to find
Barrel burner, with my current carbon barrel I assume $1/rd in barrel wear
With recent SAAMI approval we're just starting to see factory rifles chambered in it
My current load:
Alpha SRP brass. LOVE this brass
Hornady 75gr ELDM seated .020" off the lands
41gr H4350
This is a fairly mild load for the round but still performs very well and has been 1/2 MOA or better in both my gas gun and current bolt gun. Loads for each rifle had a different COAL but were both .020" off the lands in each respective barrel.
You will almost certainly need a HP bolt to run this in a gas gun to prevent pierced primers and primer flow. Gas guns can also have issues with tip damage when feeding. Small frame ARs offer much better feeding geometry for the round as the AR10 is designed around feeding 308.
Terminal Performance on Coyotes:
Couldn't be happier with the round and this bullet on coyotes. Shot dozens of them with it and have had exactly 2 that haven't dropped where they stood. One was a heart shot that managed to run about 20 yards and one was a double lung shot which is on me, not the round.
Overall it offers great performance on coyotes but shot placement still matters! You have to do your part but it is a little more forgiving than a lower energy round. It's also nice and flat shooting. Judging distance at night with thermal can be challenging. The flatter the round the further your point blank zero is going to be. I hunt mostly on flat, open ground so a flat shooting round definitely helps. To date I've taken coyotes from 60 yards to 504 yards with it.
Current rifle:
Terminus Zeus QC action
Preferred Barrel Blanks 22" 1:8 carbon fiber barrel with .080" of freebore
Triggertech Diamond 2 stage flat face trigger
MDT ACC Elite chassis
MDT GRND POD bipod in an RRS ARCA clamp
Energetic Armament Vox S with Plan B and a Rearden Brake
AGM Adder 50-640 thermal in an ADM QD mount
Warrior Tripod with Chief leveling base (most stable tripod and head I've shot off of, RRS Anvil 30 collects dust now)
SiCo Radius LRF, love this thing, even compared to demo scopes with built in LRFs I've ran
Rocking a demo Pulsar XG50 LRF
The End Results: